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Palladium-catalyzed direct alkenylation of 2-oxazolones: an entry to 3,4,5-trisubstituted 2-oxazolones.

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First Author : Lu Z

Date of Publication : 2013-01-01

Journal : The Journal of Organic Chemistry

Affiliation of Author(s) : 化学与生命科学学院

Document Type : 期刊

Volume : Vol.78

Issue : No.21

Page Number : 10894-10901

ISSN : 0022-3263

Abstract : Described herein is a novel method for the synthesis of 3,4,5-trisubstituted 2-oxazolones featuring the first Pd-catalyzed dehydrogenative alkenylation of 2-oxazolones, which is realized by employing 10 mol % of Pd(OAc)2 as the catalyst and the use of rea

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