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Regioselective and Stereoselective Entry to β,β-Disubstituted Vinyl Ethers via the Sequential Hydroboration/Suzuki–Miyaura Coupling of Ynol Ethers

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First Author : Weijian Cui

Date of Publication : 2013-01-01

Journal : The Journal of Organic Chemistry

Affiliation of Author(s) : 化学与生命科学学院

Document Type : 期刊

Volume : Vol.78

Issue : No.19

Page Number : 9815-9821

ISSN : 0022-3263

Abstract : A highly regio- and stereoselective synthesis of stereodefined β,β-disubstituted alkenyl ethers featuring the sequential hydroboration/Suzuki-Miyaura coupling of ynol ethers has been described. A number of functional groups, including OMe, Ac, CO2Et, CN,

Translation or Not : no

Pre One : A rapid and selective synthesis of α,α-fluorohalo esters via fluorohalogenative or difluorinative hydration of ynol ethers.

Next One : Palladium-catalyzed direct alkenylation of 2-oxazolones: an entry to 3,4,5-trisubstituted 2-oxazolones.

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