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Approach to highly functionalized oxazolones by a Pd-catalyzed cyclization of N-alkynyl tert-butyloxycarbamates

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First Author : Zenghui Lu

Date of Publication : 2012-01-01

Journal : Tetrahedron Letters

Affiliation of Author(s) : 化学与生命科学学院

Document Type : 期刊

Volume : Vol.53

Issue : No.27

Page Number : 3433-3436

ISSN : 0040-4039

Key Words : Oxazolones;N-Alkynyl;tert-butyloxycarbamates;Palladium;Oxypalladation;Allyl;halides

Abstract : A mild and operationally simple approach to highly functionalized oxazolones has been developed, which involves an intramolecular oxypalladation of N-alkynyl tert-butyloxycarbamates, followed by either protonolysis of the alkenyl C–Pd bond to afford 3,5-d

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