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An operationally simple approach to (E)-α-halo vinyl sulfides and their applications for accessing stereodefined trisubstituted alkenes

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First Author : Zhaozhen Yang

Date of Publication : 2013-01-01

Journal : Organic and Biomolecular Chemistry

Affiliation of Author(s) : 化学与生命科学学院

Document Type : 期刊

Volume : Vol.11

Issue : No.13

Page Number : 2175-2185

ISSN : 1477-0520

Abstract : An operationally simple and practical protocol for the synthesis of (E)-α-halo vinyl sulfides has been achieved via a highly regio- and stereoselective hydrohalogenation of alkynyl thioethers using lithium halides in HOAc or propionic acid at room tempera

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