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First Author : Lin Clement

Date of Publication : 2018-01-01

Journal : Angewandte Chemie (International ed. in English)

Affiliation of Author(s) : 物理化学研究所

Document Type : 期刊

ISSN : 1521-3773

Key Words : human;telomeres;structure-based;drug;design;chemical;probe

Abstract : Human telomeres can form DNA G-quadruplex (G4), an attractive target for anticancer drugs. Human telomeric G4s bear inherent structure polymorphism, challenging for understanding specific recognition by ligands or proteins. Protoberberines are medicinal n

Translation or Not : no