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Date of Publication : 2018-01-01
Journal : Angewandte Chemie International Edition
Affiliation of Author(s) : 物理化学研究所
Document Type : 期刊
Volume : Vol.57
Issue : No.34
Page Number : 10888-10893
ISSN : 1433-7851
Key Words : BERBERINE;*TELOMERES;*QUADRUPLEX;nucleic;acids;*GENETIC;polymorphisms;*NUCLEAR;magnetic;resonance
Abstract : Human telomeres can form DNA G‐quadruplex (G4), an attractive target for anticancer drugs. Human telomeric G4s bear inherent structure polymorphism, challenging for understanding specific recognition by ligands or proteins. Protoberberines are medicinal n
Translation or Not : no
Pre One : Molecular Recognition of the Hybrid-2 Human Telomeric G-quadruplex by Epiberberine: Insights into Conversion of Telomeric G-quadruplex Structures.
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