Personal Profile

李子颖，中共党员，博士，硕士生导师。博士毕业于福州大学，2023年加入浙江师范大学从事教学科研工作，主要从事纳米药物递送、荧光染料的设计合成及其光学诊疗应用和染料聚集体研究，通过设计新型载体材料、荧光分子构建药物递送系统，用于疾病的诊断和治疗。近5年发表学术论文11余篇，其中以第一或通讯作者在《Acta Biomaterialia》、《ACS Applied Materials＆Interfaces》、《Chemical Engineering Journal》等国外期刊发表论文7篇。

教育及工作经历：   

2023.6-至今

浙江师范大学，化学与材料科学学院，讲师

2019.9-2022.12 

福州大学，化学学院，生物化工专业，工学博士学位，导师：高瑜教授

2016.9-2019.9

福州大学，化学学院，药剂学专业，医学硕士学位，导师：高瑜教授，贾力教授

2012.9-2016.9 

福州大学，化学学院，制药工程专业，工学学士学位

研究兴趣：

1、三萜类天然产物的结构改造、新剂型设计及其抗肿瘤应用

2、近红外荧光分子的设计合成及其用于疾病的光诊疗研究

代表性论文：

1. Ziying Li*, Xugang Ji, Xiaoyi Cong, Yu Gao, Jianqing Gao*. Recent advances in nanoparticles targeting TGF-β signaling for cancer treatment. Theranostics. 2026, 16(7): 3507-3540. 

2. Ziying Li^# , Huanzhang Xie^# , Huifang Shi, Dongmiao Li, Zizhong Zhang, Haijun Chen, Yu Gao*. Triterpenoids and ultrasound dual-catalytic nanoreactor ignites long-lived hypertoxic reactive species storm for deep tumor treatment. Chemical Engineering Journal, 453 (2023), 139938.

3. Ziying Li, Huanzhang Xie, Huifang Shi, Haijun Chen, Yu Gao*. Photosensitizer dispersed on nano-sized triterpenoid matrix with deaggregation-enhanced singlet oxygen production. ACS Applied Materials & Interfaces, 15 (2023), 4973-4983. 

4. Ziying Li^# , Huifang Shi^# , Huanzhang Xie^# , Ya Yang, Yilin Zheng, Haijun Chen, Yu Gao*. Tri-component programmable nanoregulator with three-pronged penetration boosts immunotherapy of triple-negative breast cancer, Chemical Engineering Journal, 439 (2022), 135712.

5. Ziying Li, Yilin Zheng, Huifang Shi, Huanzhang Xie, Ya Yang, Fangyin Zhu, Lingjie Ke, Haijun Chen, Yu Gao*. Convenient tuning of the elasticity of self-assembled nano-sized triterpenoids to regulate their biological activities, ACS Applied Materials＆Interfaces, 13 (2021) 44065-44078.

6. Ziying Li, Lisheng Zhu, Weiqun Liu, Yilin Zheng, Xudong Li , Jinxiang Ye, Bifei Li, Haijun Chen, Yu Gao*. Near-infrared/pH dual-responsive nanocomplexes for targeted imaging and chemo/gene/photothermal tri-therapies of non-small cell lung cancer, Acta Biomaterialia, 107 (2020), 242- 259.

7. Ziying Li, Tingting Lv, Yingying Zhang, Liang Xu, Lu Zhang, Xiuying Wang, Haijun Chen, Yu Gao*. A hematoporphyrin and indocyanine green co-delivery system with NIR triggered-controllable photoactivities for photodynamic therapy, Dyes and Pigments, (2018) S0143720817326116.