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In SilicoInvestigation of the ThyroidHormone Activity of Hydroxylated Polybrominated Diphenyl Ethers.

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First Author : Haiying Yu

Journal : Chemical Research in Toxicology

Affiliation of Author(s) : 林红军

Document Type : 期刊

Volume : Vol.28

Issue : No.8

Page Number : 1538-1545

ISSN : 0893-228X

Abstract : Polybrominateddiphenyl ethers (PBDEs) have been shown to havea disruptive effect on the thyroid hormone system, and one possiblemechanism is the direct binding of their hydroxylated metabolites(HO-PBDEs) to thyroid hormone receptors (TRs). However, the ex

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