Theoretical Insight into the Catalytic Mechanism of Enoyl-CoA Hydratase
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- 作者:Zhang Yu
- 所属单位:数理与信息工程学院
- 文献类型:期刊
- 发表时间:2017-01-01
- 发表刊物:Acta Chimica Sinica
- 卷号:Vol.75
- 期号:No.5
- 页面范围:494-500
- Issn号:0567-7351
- 是否译文:否
- 关键字:Enoyl-CoA;hydratase;catalytic;mechanism;density;functional;theory;DAC-CoA;Crotonyl-CoA
- 摘要:Enoyl-CoA hydratase (ECH), which is also known as crotonase, is the second requisite enzyme in the β-oxidation pathway of fatty acid that catalyzes the syn hydration of α,β-unsaturated thiolester substrates. In this work, ECH-catalyzed hydration mechanism
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