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Copper-Catalyzed Trifluoromethylation of Alkenes with Redox-Neutral Remote Amidation of Aldehydes.

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First Author : Cheng C

Date of Publication : 2016-01-01

Journal : Org Lett

Affiliation of Author(s) : 化学与生命科学学院

Document Type : 期刊

Volume : Vol.18

Issue : No.12

Page Number : 2852-2855

ISSN : 1523-7060

Abstract : A room-temperature and one-pot synthesis of ε-CF 3 -substituted amides via the copper-catalyzed trifluoromethylation of alkenes with redox-neutral remote amidation of aldehydes is described. This reaction is featured by an unprecedented 1,5-H atom abstrac

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Pre One : Synthesis of Difluoromethylated and Phosphorated Spiro[5.5]trienones via Dearomative Spirocyclization of Biaryl Ynones.

Next One : Copper-catalyzed cascade annulation of unsaturated α-bromocarbonyls with enynals: a facile access to ketones from aldehydes

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