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Copper-Catalyzed β-Selective Hydroborylation of Ynamides: A Facile Access to (E)-β-Alkenylamide Boronates

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First Author : Yihui Bai

Date of Publication : 2015-01-01

Journal : Asian Journal of Organic Chemistry

Affiliation of Author(s) : 化学与生命科学学院

Document Type : 期刊

Volume : Vol.4

Issue : No.7

Page Number : 626-629

ISSN : 2193-5807;2193-5815

Key Words : alkenylamide;boronates;bis(pinacolato)diboron;copper;hydroboration;ynamides

Abstract : A Cu-catalyzed, highly β-selective borylation of ynamides with bis(pinacolato)diboron as the hydroboration reagent is reported, giving (E)-β-alkenylamide boronates in excellent regio- and stereoselectivity under mild reaction conditions, which provides a

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