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Direct access to 2-amino-5-azidomethylfurans through palladium-catalyzed azidative cycloisomerization of homoallenyl amides.

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First Author : Huang Q

Date of Publication : 2016-01-01

Journal : Org Biomol Chem

Affiliation of Author(s) : 化学与生命科学学院

Document Type : 期刊

Volume : Vol.14

Issue : No.36

Page Number : 8557-8563

ISSN : 1477-0520;1477-0539

Abstract : A room temperature, efficient, and palladium-catalyzed azidative cycloisomerization of homoallenyl amides using TMSN 3  as the azidation reagent and PhI(O 2 CCF 3 ) 2  as the oxidant is described, producing a variety of 2-amino-5-azidomethylfurans in mode

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