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Copper-catalyzed direct thiolation of xanthines and related heterocycles with disulfides

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First Author : Zuying He

Date of Publication : 2013-01-01

Journal : Tetrahedron Letters

Affiliation of Author(s) : 化学与生命科学学院

Document Type : 期刊

Volume : Vol.54

Issue : No.44

Page Number : 5907-5910

ISSN : 0040-4039

Key Words : Xanthines;Thiolation;Copper;Disulfides

Abstract : A novel copper-catalyzed, base-free direct thiolation of xanthines and related heterocycles is described, featuring the use of inexpensive Cu(OAc) 2 ?¡èH 2 O as the catalyst, O 2  as a clean and cheap oxidant, and easy-to-handle disulfides as the thiolati

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