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Highly mono-selective ortho-methylthiolation of benzamides via cobalt-catalyzed sp<sup>2</sup> C–H activation

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First Author : Liang Hu

Date of Publication : 2018-01-01

Journal : Organic Chemistry Frontiers

Affiliation of Author(s) : 化学与生命科学学院

Document Type : 期刊

Volume : Vol.5

Issue : No.2

Page Number : 216-221

ISSN : 2052-4129

Abstract : A highly mono-selective ortho-methylthiolation of benzamides was achieved via Co-catalyzed coupling of benzamides with DMSO. The reaction employs an 8-aminoquinoline group as the bidentate directing group and DMSO as the methylthiolation source. Instead o

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