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ChemInform Abstract: A Regio- and Stereoselective Entry to (Z)-β-Halo Alkenyl Sulfides and Their Applications to Access Stereodefined Trisubstituted Alkenes.

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First Author : Ge Liu

Date of Publication : 2014-01-01

Journal : ChemInform

Affiliation of Author(s) : 化学与生命科学学院

Document Type : 期刊

Volume : Vol.45

Issue : No.37

Key Words : mercaptans,;thioethers;(benzene;compounds);e/z-selectivity;(incl.;e/z-isomerism);C-C;bond;formation;mercaptans,;thioethers;(acyclic;compounds);alkenes;(acyclic;compounds);alkenes;(benzene;compounds)

Abstract : The base-promoted hydrothiolation of bromoalkyne (I) leads to (Z)-bromo vinylic sulfides (III), which are converted into (Z)-trisubstituted alkenes (VII) and (VIII) by Suzuki coupling and a subsequent reaction of resulting alkenyl sulfides (V) with Grigna

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