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Enhanced Binding of a Non-hydrogen Bond Ligand to DNA by Introducing an Apurine/Apyrimidine Site

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First Author : Yong SHAO

Date of Publication : 2009-01-01

Journal : Chinese Journal of Chemistry

Affiliation of Author(s) : 物理化学研究所

Document Type : 期刊

Volume : Vol.27

Issue : No.6

Page Number : 1117-1122

ISSN : 1001-604X

Key Words : DNA;apurine/apyrimidine;site;molecular;recognition;binding;specificity;non-hydrogen;bond;ligand

Abstract : Intercalators are well known for their DNA binding specificity by inserting between base pairs, whereas the binding event occurring to apurine/apyrimidine site (AP site)-containing DNA for this type of noncovalent interaction is still not highlighted alth

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