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Triplex-forming oligonucleotide as a lighting-up switch for a DNA abasic site-binding fluorescent ligand

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First Author : Ziyue Ni

Date of Publication : 2018-01-01

Journal : Journal of Luminescence

Affiliation of Author(s) : 物理化学研究所

Document Type : 期刊

Volume : Vol.198

Page Number : 193-197

ISSN : 0022-2313

Key Words : DNA;Triplex;Ligand;Abasic;site;Fluorescence

Abstract : DNA apurinic/apyrimidinic site (AP site) has received much attention due to its importance in disease evolution and development of selective genetic drugs. Fluorescence technique has been widely employed in identifying the AP sequence environment using fl

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