个人简介：

孙洪杰，博士，副教授，硕士生导师，金华市食品安全委员会咨询专家组成员。近年来主要从事消毒副产物等新兴污染物的环境行为及健康风险等方向的研究工作（图1和）。目前已在环境领域Environment International, Environmental Science & Technology, Journal of Hazardous Materials, Environmental Pollution, Science of Total environment, Environmental Research, Chemosphere, Environmental toxicology and chemical 等期刊上发表SCI期刊论文60余篇，其中以第一/通讯作者身份发表SCI论文30余篇，SCI引用近3000次，H-index为29（参见https://scholar.google.com.hk/citations?user=O1gWQ_sAAAAJ&hl=zh-CN&oi=ao）。目前已申请专利5项，主持国家及其它省部级项目7项。同时应邀担任Journal of Environmental and Public Health 杂志编委, fishes 杂志专刊编辑及 Water Res. J. Hazard. Mater., Environ.Pollut.等多个国际期刊的审稿人。

图 1. 新型消毒副产物3-BCZ的心脏毒性及机制的相关研究

承担科研项目情况

2017.01-2018.12，浙江省教育厅项目,金华市孝顺镇废弃电池污染场地的检测及健康风险评估,  主持

2017.04-2019.04,   金华市公益项目, “五水共治”工程后金华市水体水质的健康安全风险评估,  主持

2018.01-2020.12，国家自然科学基金项目，基于转录组学解析砷对甲状腺内分泌系统的干扰机制，主持

2019.01-2021.12,  浙江省公益项目，饮用水中消毒副产物的健康风险评价及防控, 主持

近年来代表性论文：

1. Sun Hongjie*, Liu Yingying, Wu Chunxiu, Ma Lena Q., Guan Dongxing, Hong Huachang, Yu Haiying, Lin Hongjun, Huang Xianfeng, Gao Peng, 2024. Dihalogenated nitrophenols in drinking water: Prevalence, resistance to household treatment, and cardiotoxic impact on zebrafish embryo. Eco-Environmental & Health, 3(2): 183-191. (Front Cover) 

2. Liu Yingying, Jin Xudong, Ye Yanan, Xu Zeqiong, Du Zhongkun, Hong Huachang, Yu Haiying, Lin Hongjun, Huang Xianfeng, Sun Hongjie*. 2024. Emerging disinfection byproductions 3-Bromine carbazole induces cardiac developmental toxicity via aryl hydrocar bon receptor activation in zebrafish larvae. Environmental Pollution. 346, 123609.

3. Zhu Wenting, Liu Yingying, Xuan Xiongzhi, Xu Zeqiong, Gao Peng, Jin Zhigang, Hong Huachang, Sun Hongjie*. 2024. Dihalogenated nitrophenols exposure induces developmental neurotoxicity in zebrafish embryos. Ecotoxicology and Environmental Safety. 277, 116359.

4. Dong Mingyue, Wang Jieyu, Liu Yingying, He Qianfeng, Sun Hongjie*, Xu Zeqiong, Hong Huachang, Lin Hongjun, Gao Peng, 2023. 3-Bromocarbazole-Induced Developmental Neurotoxicity and Effect Mechanisms in Zebrafish. ACS ES&T water 3, 24781-2480.

5. Dong Mingyue, Ding Yan, Liu Yingying, Xu Zeqiong, Hong Huachang, Sun Hongjie*, Huang X., Yu X. and Chen Q., 2023. Molecular insights of 2,6-dichlorobenzoquinone-induced cytotoxicity in zebrafish embryo: Activation of ROS-mediated cell cycle arrest and apoptosis. Environmental toxicology 38(3), 694-700.

6. Sun Hongjie, Ding Song, Guan Dongxing, Ma Lena Q. 2022. Nrf2/keap1 pathway in countering arsenic-induced oxidative stress in mice after chronic exposure at environmentally-relevant concentrations. Chemosphere, 303, 135256.

7. 滕晓强，陆宏峰，郭心月，高畅，罗钦方，张瑜，洪华嫦，孙洪杰*，2020. 二氯苯醌对斑马鱼胚胎的发育及超氧化物歧化酶的影响. 环境科学学报  DOI: 10.13671/j.hjkxxb.2020.0074.

8. Sun Hongjie*, Zhang Jingying, Wang Qiang, Zhu engao, Chen Wenrong, Lin Hongjun, Chen Jianrong, Hong Huachang, 2019. Environmentally relevant concentrations of arsenite induces developmental toxicity and oxidative responses in the early life stage of zebrafish. Environmental Pollution 254, 113022.

9. Zhang Yu, Sun Hongjie*, Zhang Jing-Ying, Ndayambaje Emmanuel, Lin Hongjun, Chen Jianrong, Hong Huachang, 2019. Chronic exposure to dichloroacetamide induces biochemical and histopathological changes in the gills of zebrafish, Environmental Toxicology, 34(7):781-787 (Front Cover).

10. Sun Hongjie, Zhang Yu, Zhang Jing-Ying, Lin Hongjun, Chen Jianrong, Hong Huachang*. 2019. The toxicity of 2,6-dichlorobenzoquinone on the early life stage of zebrafish: a survey on the endpoints at developmental toxicity, oxidative stress, genotoxicity and cytotoxicity. Environmental Pollution. 245，719-724

学生指导

指导陈依雯等学生参加2023年浙江省大学生环境生态科技创新大赛，并获得一等奖；

指导沈佳乐等学生参加2022年浙江省大学生环境生态科技创新大赛，获二、三等奖各一项；

指导余昱瑶等学生参加2022年全国大学生节能减排社会实践大赛，并获得三等奖。

教学情况

为本科生主讲课程有《环境生态学》、《环境毒理学》及《环境毒理学实验》。