朱钢国

基本信息Personal Information

教授 博士生导师 硕士生导师

曾获荣誉 : 科研获奖: 1、2015年浙江省自然科学奖三等奖:杂原子取代炔烃的亲核金属化反应方法学研究(第一完成人); 2、2012年度浙江省高校优秀科研成果奖一等奖:杂原子取代炔烃的亲核钯化反应方法学研究(第一完成人)。

性别 : 男

毕业院校 : 中科院上海有机化学研究所

学历 : 博士研究生毕业

学位 : 博士学位

在职信息 : 在岗

所在单位 : 化学与生命科学学院

入职时间 : 2008年12月04日

学科 : 化学

联系方式 : 0579-82282640

Email :

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个人简介Personal Profile

主要经历如下:

19969月-20007月:浙江师范大学化学系,理学学士。

20009月-20057月:中科院上海有机化学研究所理学博士,导师张兆国教授。

20059月-200710月:师从美国普渡大学诺贝尔化学奖得主Negishi教授博士后研究,完成了spongidepsinhexamethyldocosane等天然产物的全合成。

200711月-200810月:美国印第安纳大学博士后研究。

200812月-至今:浙江师范大学化学系任教。现为教授硕士生导师、化学与生命科学学院副院长、先进催化材料教育重点实验室负责人2009年入选浙江省“151”人才第三层次培养对象2013年入选浙江省高校中青年学科带头人,2016年入选浙江省“151”人才工程第二层次培养对象、浙江师范大学“双龙学者”特聘教授。已发表Angew. Chem. Int. Ed.Chem. Sci.Org. Lett.Chem. Commun.Adv. Synth. Catal.J. Org. Chem.SCI论文70篇,SCI引用1100,授权发明专利9件,先后主持国家自然科学基金3项、浙江省自然科学杰出青年基金等省部级项目3项,完成企业横向项目2项,主要从事过渡金属催化的氟化反应、自由基反应和生理活性的天然产物全合成研究


科研获奖:

      12015年浙江省自然科学奖三等奖:杂原子取代炔烃的亲核金属化反应方法学研究(第一完成人);

      22012年度浙江省高校优秀科研成果奖一等奖:杂原子取代炔烃的亲核钯化反应方法学研究(第一完成人)。

主持项目:

1、 国家自然科学基金面上项目:过渡金属催化的醛直接转化为酮的自由基反应研究(21672191)

2、 浙江省公益性技术应用研究计划项目:2-氨基呋喃化学品的催化合成技术研究(2015C31030)

3、 国家自然科学基金面上项目:基于1,2-双官能团化烯烃的偶联反应选择性合成多取代烯烃(21172199),已结题;

4、 浙江省杰出青年基金:1--1-硫代烯烃的立体选择性合成及其三取代烯烃的构建(LR12B02001) ,已结题;

5、 国家自然科学基金青年基金:偶极烯丙基钯的环加成反应研究(20902084) ,已结题;

6、 浙江省钱江人才计划项目:抗禽流感药物达菲的合成工艺研究(2010R10016) ,已结题;

7、 完成企业横向项目2项。

发表文章

2018

1. Visible-light induced three-component alkynyl-difluoroalkylation of unactivated alkenes, Jin, W.; Wu, M.; Xiong, Z. Zhu, G.* Chem. Commun. 2018, 54, DOI: 10.1039/C8CC03105C.

2. Synthesis of Difluoromethylated and Phosphorated Spiro[5.5]trienones via Dearomative Spirocyclization of Biaryl Ynones, Zhang, Y.*; Zhang, J.; Hu, B.; Ji, M.; Ye, S.; Zhu, G.* Org. Lett. 2018, 20, 2988-2992. 

3. Photocatalytic acylarylation of unactivated alkenes with diaryliodonium salts toward indanones and related compounds, Chen, Y.; Shu, C.; Luo, F.; Xiao, X.;* Zhu, G.* Chem. Commun. 2018, 54, 5373-5376.

4. Intermolecular Oxidative Radical Addition to Aromatic Aldehydes: Direct Access to 1,4- and 1,5-Diketones via Silver-Catalyzed Ring-Opening Acylation of Cyclopropanols and Cyclobutanols, Che, C.; Qian, Z.; Wu, M.; Zhao, Y.; Zhu, G.* J. Org. Chem. 2018, 83, 5665-5673.

5. Nickel-Catalyzed Remote Arylation of Alkenyl Aldehydes Initiated by Radical Alkylation with Tertiary α-Carbonyl Alkyl Bromides, Jin, W.; Zhou, Y.; Zhao, Y.; Ma, Q.; Kong, L.; Zhu, G.* Org. Lett. 2018, 20, 1435-1438.

6. Palladium-Catalyzed Site-Selective sp3 C-H Bond Thiocyanation of 2-Aminofurans, Chen, Y.; Wang, S.; Jiang, Q.; Cheng, C.; Xiao, X.;* Zhu, G.* J. Org. Chem. 2018, 83, 716-722.

2017

7. Preparation of 2-Amino-5-homoallylfurans via Palladium-Catalyzed Tandem Cycloisomerization/Heck-Type Coupling of Homoallenyl Amides with Allyltrialkylsilanes, Zhang, J.; Wu, M.; Lu, W.; Wang, S.; Zhang, Y.; Cheng, C.;* Zhu, G.* J. Org. Chem. 2017, 82, 11134-11140.

8. Palladium-catalyzed tandem cyclization/sulfonylation of homoallenyl amides with sodium sulfinates, Wan, Y.; Zhang, J.; Chen, Y.; Kong, L.; Luo, F.;* Zhu, G.* Org. Biomol. Chem. 2017, 15, 7204-7211.

9. Copper-Catalyzed Radical Cascade Difluoromethylation/Cyclization of 2-(3-Arylpropioloyl)benzaldehydes: A Route to Difluoromethylated Naphthoquinones, Zhang, Y.*; Ye, S.; Ji, M.; Li, L.; Guo, D.; Zhu, G. J. Org. Chem. 2017, 82, 6811-6818.

10. Visible Light-Induced Tandem Radical Addition-Cyclization of Alkenyl Aldehydes Leading to Indanones and Related Compounds, Lu, D.; Wan, Y.; Kong, L.; Zhu, G.* Org. Lett. 2017, 19, 2929-2932.

11. Copper-catalyzed acyltrifluoromethylation of alkenes: rapid access to trifluoroethyl indanones and related compounds, Liu, Z.; Bai, Y.; Zhang, J.; Yu, Y.; Tan, Z.; Zhu, G.* Chem. Commun. 2017, 53, 6440-6443.

12. Palladium-Catalyzed Remote Aryldifluoroalkylation of Alkenyl Aldehydes, Nie, X.; Cheng, C.; Zhu, G.* Angew. Chem. Int. Ed. 2017, 56, 1898-1902.

13. Synthesis of Trifluoromethylated Naphthoquinones via Copper-Catalyzed Cascade Trifluoromethylation/Cyclization of 2-(3-Arylpropioloyl)benzaldehydes, Zhang, Y.;* Guo, D.(本科生); Ye, S.; Liu, Z.; Zhu, G.* Org. Lett. 2017, 19, 1302-1305.

14. Copper-catalyzed borylative cyclization of 1,n-enynyl phosphates leading to five- to eight-membered cyclic 1,4-dienyl boronates, Zhang, F.; Wang, S.; Liu, Z.; Bai, Y.;* Zhu, G.* Tetrahedron Lett. 2017, 58, 1448-1452.

2016

15. Synthesis of (E)-α,β-Unsaturated Carbonyls via Silver-Catalyzed Tandem Epoxide Rearrangement/Intermolecular Carbonyl-Heteroalkyne Metathesis, Zhu, H.; Jin, W.; He, J.; Zhang, Y.*; Zhu, G.* Adv. Synth. Catal. 2016, 358, 3730-3735.

16. Copper-catalyzed cascade annulation between α-bromocarbonyls and biaryl or (Z)-arylvinylacetylenes enabling a direct synthesis of dibenzocycloheptanes and related compounds, Lu, D.; Wan, Y.; Kong, L.; Zhu, G.* Chem. Commun. 2016, 52, 13971-13974.

17. Copper-Catalyzed Trifluoromethylation of Alkenes with Redox-Neutral Remote Amidation of Aldehydes, Cheng, C.; Liu, S.; Lu, D.; Zhu, G.* Org. Lett. 2016, 18, 2852-2855.

18. Copper-catalyzed cascade annulation of unsaturated α-bromocarbonyls with enynals: a facile access to ketones from aldehydes, Che, C.; Huang, Q.; Zheng, H.; Zhu, G.* Chem. Sci. 2016, 7, 4134-4139.

19. Direct access to 2-amino-5-azidomethylfurans through palladium-catalyzed azidative cycloisomerization of homoallenyl amides, Huang, Q.(本科生); Zheng, H.; Liu, S.; Kong, L.; Luo, F.*; Zhu, G.* Org. Biomol. Chem. 2016, 14, 8557-8563.

20. HOTf-Catalyzed, Solvent-free Oxyarylation of Ynol Ethers and Thioethers, Hu, L.; Cui, Q.; Chen, X.; Tan, Z.*; Zhu, G.* J. Org. Chem. 2016, 81, 4861-4868.

21. Copper-catalyzed coupling of 2-vinyl benzaldehydes with 3-alkenyl 2-bromocarbonyls for the rapid construction of 3,4-cyclopenta-1-tetralones, Zhu, H.; Nie, X.; Huang, Q.; Zhu G.* Tetrahedron Lett. 2016, 57, 2331-2335.

22. Highly mono-selective ortho-trifluoromethylation of benzamides via 8-aminoquinoline assisted Cu-promoted C-H activations, Hu, L.; Chen, X.; Gui, Q.; Tan, Z.*, Zhu, G. Chem. Commun. 2016, 52, 6845-6848. 

2015

23. A rapid and selective synthesis of α,α-fluorohalo esters via fluorohalogenative or difluorinative hydration of ynol ethers, Hu, L.; Che, C.; Tan, Z.;* Zhu, G.* Chem. Commun. 2015, 51, 16641-16644.

24. Construction of 1-Naphthols via Benzannulation Based on the Reaction of Aryl tert-Butyl Ynol Ethers with Ynamides or Ynol Ethers, Bai, Y.; Yin, J.; Liu, Z.; Zhu, G.* J. Org. Chem. 2015, 80, 10226-10233.

25. Copper-Catalyzed trans-Carbohalogenation of Terminal Alkynes with Functionalized Tertiary Alkyl Halides, Che, C.; Zheng, H.; Zhu, G.* Org. Lett. 2015, 17, 1617-1620.

26. Palladium-Catalyzed Cycloisomerization and Aerobic Oxidative Cycloisomerization of Homoallenyl Amides: A Facile and Divergent Approach to 2-Aminofurans, Cheng, C.; Liu, S.; Zhu, G.* Org. Lett. 2015, 17, 1581-1584. 

27. Copper-catalyzed regio- and stereoselective hydroallylation of thioalkynes with allylboronates: a facile and convenient synthesis of 1,4-dienes, Kong, W.; Che, C.; Kong, L.*; Zhu, G.* Tetrahedron Lett. 2015, 56, 2780-2782.

28. Copper-Catalyzed β-Selective Borylation of Ynamides: A Facile Access to (E)-β-Alkenylamide Boronates, Bai, Y.*; Zhang, F.; Shen, J.; Luo, F.; Zhu, G.* Asian J. Org. Chem. 2015, 4, 626-629 (Dedicated to Prof. Ei-ichi Negishi on the occasion of his 80th birthday)

29. Divergent Synthesis of 2-Aminofurans via Palladium-Catalyzed Acetoxylative, Alkoxylative, and Hydroxylative Cycloisomerization of Homoallenyl Amides, Cheng, C.; Liu, S.; Zhu, G.* J. Org. Chem. 2015, 80, 7604-7612.

2014

30. Palladium-Catalyzed Cross Addition of Terminal Alkynes to Aryl Ynamides: An Unusual trans-Hydroalkynylation Reaction, Liu, G.; Kong, W.; Che, J.; Zhu, G.* Adv. Synth. Catal. 2014, 356, 3314-3318.

31. Preparation of (Z)-α,β-Disubstituted Enamides via Palladium-Catalyzed Addition of Boronic Acids to Ynamides, Yang, Y.; Wang, L.; Zhang, F.; Zhu. G.* J. Org. Chem. 2014, 79, 9319-9324.  

32. Silver-Catalyzed Regio- and Stereoselective Addition of Carboxylic Acids to Ynol Ethers, Yin, J.; Bai, Y.; Mao, M.; Zhu. G.* J. Org. Chem. 2014, 79, 9179-9185.  

33. Silver-promoted trans-hydrofluorination of ynamides: a regio- and stereoselective approach to (Z)-α-fluoroenamides, Che, J.(本科生); Li, Y.; Zhang, F.; Zheng, R.*; Bai, Y.; Zhu. G.* Tetrahedron Lett. 2014, 55, 6240-6242.  

34. Pd-Catalyzed Regio- and Stereoselective Addition of Boronic Acids to Silylacetylenes: A Stereodivergent Assembly of β,β-Disubstituted Alkenyl Silanes and Alkenyl Halides, Kong, W.; Che, C.; Wu, J.; Ma, L.; Zhu, G.* J. Org. Chem. 2014, 79, 5799-5805.  

35. Palladium-Catalyzed Hydroarylation, Hydroalkenylation, and Hydrobenzylation of Ynol Ethers with Organohalides: A Regio- and Stereoselective Entry to α,β- and β,β-Disubstituted Alkenyl Ethers, Cui, W.; Ying, J.; Zheng, R.; Cheng, C.; Bai, Y. Zhu, G.* J. Org. Chem. 2014, 79, 3487-3493.  

36. An unprecedented Pd-catalyzed trans-addition of boronic acids to ynamides. Yang, Y.; Wang, L.; Zhang, J.; Jin, Y.; Zhu, G.* Chem. Commun. 2014, 50, 2347-2349.

37. Synthesis of cis-1,2-dichlorovinylsulfones via Fe-catalyzed regio- and stereoselective addition of sulfonyl chlorides to aromatic chloroalkynes. Wang, L.; Zhu, H.; Che, J.; Yang, Y.*; Zhu, G.* Tetrahedron Lett. 2014, 55, 1011-1013.  

38. Synthesis of (Z)-1-Thio- and (Z)-2-Thio-1-alkenyl Boronates via Copper-Catalyzed Regiodivergent Hydroboration of Thioacetylenes: An Experimental and Theoretical Study. Zhu, G.*; Kong, W.; Feng, H.; Qian, Z.* J. Org. Chem. 2014, 79, 1786-1795.

39. A regio- and stereoselective entry to (Z)-β-halo alkenyl sulfides and their applications to the access of stereodefined trisubstituted alkenes. Liu, G.; Kong, L.; Shen, J.; Zhu, G.* Org. Biomol. Chem. 2014, 12, 2310-2321. 

2013

40. Palladium-Catalyzed Direct Alkenylation of 2-Oxazolones: An Entry to 3,4,5-Trisubstituted 2-Oxazolones, Lu, Z.; Luo, F.; Wang, L.; Zhu, G.* J. Org. Chem. 2013, 78, 10894-10901.

41. Pd-catalyzed addition of boronic acids to ynol ethers: a highly regio- and stereoselective synthesis of trisubstituted vinyl ethers. Bai, Y.; Yin, J.; Kong, W.; Mao, M.; Zhu, G.* Chem. Commun. 2013, 49, 7650-7652.

42. Regioselective and Stereoselective Entry to β,β-Disubstituted Vinyl Ethers via the Sequential Hydroboration/SuzukiMiyaura Coupling of Ynol Ethers. Cui, W.; Mao, M.; He, Z.; Zhu, G.* J. Org. Chem. 2013, 78, 9815-9821.

43. Copper-catalyzed direct thiolation of xanthines and related heterocycles with disulfides. He, Z. (本科生); Luo, F.;* Li, Y.; Zhu, G.* Tetrahedron Lett. 2013, 54, 5907-5910.

44. An operationally simple approach to (E)-α-halo vinyl sulfides and their applications for accessing stereodefined trisubstituted alkenes. Yang, Z.(本科生); Chen, X.; Kong, W.; Xia, S.; Zheng, R.; Luo, F.; Zhu, G.* Org. Biomol. Chem. 2013, 11, 2175-2185.

2012

45. Highly stereoselective synthesis of (Z)-1,2-dihaloalkenes by a Pd-catalyzed hydrohalogenation of alkynyl halides. Zhu, G.*; Chen, D.; Wang, Y.; Zheng, R. Chem. Commun. 2012, 48, 5796-5798. 

46. Preparation of 3,4,5-Trisubstituted Oxazolones by Pd-Catalyzed Coupling of N-Alkynyl tert-Butyloxycarbamates with Aryl Halides and Related Electrophiles. Lu, Z.; Cui, W.; Xia, S.; Bai, Y.; Luo, F.; Zhu, G.* J. Org. Chem. 2012, 77, 9871-9877. 

47. A Facile Access to 3,5-Disubstituted Oxazolones Featuring a Cu-catalyzed Cyclization of N-Alkynyl tert-Butyl Carbamates. Lu, Z.; Yang, Z.; Cui, W.; Zhu, G.* Chem. Lett. 2012, 41, 636-638.

48. Approach to highly functionalized oxazolones by a Pd-catalyzed cyclization of N-alkynyl tert-butyloxycarbamates. Lu, Z.; Xu, X.; Yang, Z.; Kong, L.*; Zhu, G.* Tetrahedron Lett. 2012, 53, 3433-3436. 

49. A Facile Method for the Synthesis of 3-Alkyloxindole. Du, T.; Zhu, G.*; Zhou, J.* Lett. Org. Chem. 2012, 9, 225-232.

2011

50. Palladium-catalyzed haloallylation of aromatic ynol ethers with allyl chlorides: a highly regio- and stereoselective approach to (1E)-α-chloroenol ethers. Cai, H.(本科生); Yuan, Z.; Zhu, W.; Zhu, G.* Chem. Commun. 2011, 47, 8682-8684. 

51. Palladium-catalyzed highly regio- and stereoselective synthesis of (1E)- or (1Z)-1,2-dihalo-1,4-dienes via haloallylation of alkynyl halides. Chen, X.; Kong, W.; Cai, H.; Kong, L.; Zhu, G.* Chem. Commun. 2011, 47, 2164-2166. 

52. Palladium-Catalyzed Dienylation of Haloalkynes Using 2,3-Butadienyl Acetates: A Facile Access to (1Z)-1,2-Dihalo-3-vinyl-1,3-dienes. Chen, D.; Chen, X.; Lu, Z.; Cai, H.; Shen, J.; Zhu, G.* Adv. Synth. Catal. 2011, 353, 1474-1478. 

53. Synthesis of Multisubstituted Enamides via Pd-Catalyzed Chloroallylation of Ynamides. Lu, Z.; Kong, W.; Yuan, Z.; Zhao, X.; Zhu. G.* J. Org. Chem. 2011, 76, 8524-8529. 

54. Palladium-Catalyzed Coupling of Haloalkynes with Allyl Acetate: A Highly Regio- and Stereoselective Synthesis of (Z)-β-Haloenol Acetates. Chen, X.; Chen, D.; Lu, Z.; Kong, L.; Zhu, G.* J. Org. Chem. 2011, 76, 6338-6343. 

55. Synthesis of cis-1,2-Dihaloalkenes Featuring Palladium-Catalyzed Coupling of Haloalkynes and α,β-Unsaturated Carbonyls. Chen, D.; Cao, Y.; Yuan, Z.; Cai, H.; Zheng, R.; Kong, L.; Zhu, G.* J. Org. Chem. 2011, 76, 4071-4074. 

2010

56. Highly efficient and diastereoselective synthesis of 1,3-oxazolidines featuring a palladium-catalyzed cyclization reaction of 2-butene-1,4-diol derivatives and imines. Chen, D.; Chen, X.; Du, T.; Kong, L.; Zheng, R.; Zhen, S.; Wen, Y.; Zhu, G.* Tetrahedron Lett. 2010, 51, 5131-5133.

博士及博士后阶段

57. A Tunable Mimics of Pyridoxal-5’-phosphate (PLP) Catalyst for Schiff Base Exchange and Amine Deprotonation. Felten, A.; Zhu, G.; Aron, Z.* Org. Lett. 2010, 12, 1099-1101.

58. Efficient and Selective Synthesis of (S,R,R,S,R,S)-4,6,8,10,16,18-Hexamethyldocosane via Zr-Catalyzed Asymmetric Carboalumination of Alkenes (ZACA Reaction). Zhu, G.; Liang, B.; Negishi, E.* Org. Lett. 2008, 10, 1099-1101.

59. 1,4-Pentenyne as a Five-Carbon Synthon for Efficient and Selective Syntheses of Natural Products Containing 2,4-Dimethyl-1-penten-1,5-ylidene and Related Moieties via Zr-Catalyzed Carboalumination of Alkynes and Alkenes. Zhu, G.; Negishi, E.* Chem. Eur. J. 2008, 14, 311-318.

60. Fully Reagent-Controlled Asymmetric Synthesis of (–)-Spongidepsin via the Zr-Catalyzed Asymmetric Carboalumination of Alkenes (ZACA Reaction). Zhu, G.; Negishi, E.* Org. Lett. 2007, 9, 2771-2774.

61. Zirconium-Catalyzed Asymmetric Carboalumination of Alkenes (ZACA)_Lipase-Catalyzed Acetylation Synergy. Huang, Z.; Tan, Z.; Novak, T.; Zhu, G.; Negishi, E.* Adv. Synth. Catal. 2007, 349, 539-545.

62. Zirconium-Catalyzed Methylalumination of Heterosubstituted Arylethynes. Factors Affecting the Regio-, Stereo-, and Chemoselectivities. Wang, G.; Zhu, G.; Negishi, E.* J. Organomet. Chem. 2007, 692, 4731-4736.

63. Palladium-Catalyzed Cyclization via Carbopalladation and Acylpalladation. Negishi, E.*; Wang, G.; Zhu, G. Topics in Organometallic Chemistry, 2006, 19, 1-48. 

64. Transition Metal-Catalyzed Intramolecular Enyne Cyclization Reaction. Zhang, Z.*; Zhu, G.; Tong, X.; Wang, F.; Xie, X.; Wang, J.; Jiang, L. Curr. Org. Chem. 2006, 10, 1457-1478.

65. Palladium-Catalyzed Tandem Cyclization/Suzuki Coupling of 1,6-Enynes: Reaction Scope and Mechanism. Zhu, G.; Tong, X.; Cheng, J.; Sun, Y.; Li, D.; Zhang, Z.* J. Org. Chem. 2005, 70, 1712-1717.

66. cis-Chloropalladation of 1,6-Enynes. Zhu, G.; Zhang, Z.* J. Org. Chem. 2005, 70, 3339-3341.

67. A Concise Synthesis of 2-Diarylphosphino-20-methoxy-1,10-binaphthalenes (MOPs) by Simple Resolution. Luo, Y.; Wang, F.; Zhu, G.; Zhang, Z.* Tetrahedron Asymmetry 2004, 15, 15-17.

68. Palladium-Catalyzed Tandem Cyclization/Suzuki Coupling of 1,2,7-trienes. Zhu, G.; Zhang, Z.* Org. Lett. 2004, 6, 4041-4044.

69. Palladium-Catalyzed Tandem Cyclization/Suzuki Coupling of 1,6-Enynes. Zhu, G.; Zhang, Z.* Org. Lett. 2003, 5, 3645-3648.

学术报告:

1. 醛基的氧化自由基加成反应研究,第31届中国化学会学术年会,浙江杭州,2018.0507

2. 远程醛基碳-氢键直接官能团化反应研究,第十届全国有机化学学术会议,广东深圳,2017.12.19

3. 醛直接转化为酮的催化自由基反应研究,第十五届全国均相催化学术讨论会,浙江杭州,2017.09.28

4. Transition-Metal-Catalyzed Radical Transformation of Aldehydes for the Synthesis of Carbonyl Compounds第一届全国有机自由基化学会议苏州,2017.11.04

授权专利:

1、 顺式-1--2-氯代烯烃及其制备方法和应用,朱钢国、陈东旭,专利号:ZL 201210004757.9,授权时间:2013.11.27

2、 一种莽草酸的合成方法,朱钢国、崔伟剑、夏思苑、何祖莺,专利号:ZL 201210094437.7,授权时间:2013.11.27

3、 一种3,4,5-三取代噁唑-2-合成方法,朱钢国、卢增辉、刘鸽、罗芳、夏思苑,专利号:ZL 201210283568.X,授权时间:2014.11.05

4、 一种利用顺式-1--2-氯代烯烃合成维生素A的方法,朱钢国,陈东旭,专利号:ZL 201310350098.9,授权时间:2014.11.05

5、 一种替马罗汀的合成方法,朱钢国、李英龙、金雅丽、金发根、吴平、楼益义,专利号:ZL 201310362839.5,授权时间:2015.01.14

6、 一种奥司他韦的合成方法,朱钢国、杜思全、章洁妮、程存归,专利号:ZL 201410102788.7,授权时间:2015.05.27

7、 一种8-硫杂黄嘌呤化合物的制备方法,罗芳、何祖莺、朱钢国、李英龙,专利号:ZL 201310186179.X,授权时间:2015.07.08

8、 一种8-芳基或烯基取代的黄嘌呤化合物的制备方法,罗芳、金雅莉、何祖莺、朱钢国,专利号:ZL 201310186221.8,授权时间:2015.06.24

9、 一种多环酮的制备方法,朱钢国、车超、黄倩雯、郑汉良,专利号:ZL 201510874900.3,授权时间:2018.03.20

指导学生:

 1校优秀硕士学位论文:陈东旭(2012)、卢增辉(2013)、崔伟剑(2014)、孔伟(2015)、印靖(2015)、车超(2016)、刘水有(2016),聂新亮(2017)、卢丹阳(2017)。

2夏思苑等,杂原子取代炔烃的氢卤化反应研究及其应用,第十三届大学生“挑战杯”竞赛浙江省一等奖、全国二等奖。


Tel0579-82282640E-mail: gangguo@zjnu.cn



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