王丹丹，博士，现为浙江师范大学化学与生命科学学院讲师，硕士生导师。2020年12月博士毕业于中国科学院长春应用化学研究所电分析国家重点实验室。长期从事纳米孔电化学在单分子、单细胞检测方面的研究工作，相关工作先后发表在ACS nano，Chem. Commun., Anal. Chim. Acta等期刊上。主持国家自然科学基金、浙江省自然科学基金、金华市科技局重点项目等科研项目6项。

主要研究方向

• 纳米孔电化学在单分子检测方面的传感应用

• 固态仿生纳米通道用于分子/离子传输的研究

• 基于核酸结构的光/电生物传感器的研究

主持或参与的科研项目

 1. 国家自然科学基金青年项目，Plasmonic纳米孔光电同步传感用于肿瘤细胞外泌体单颗粒多参数检测的研究，2024-2026，主持

 2. 浙江省自然科学基金青年探索类项目，酶功能化的无线纳米 孔电极用于亚细胞水平上ROS超灵敏检测的研究，2022-2024，主持

 3. 金华市科技社发类重点项目，基于固态纳米孔光电同步传感策略检测胰腺癌外泌体单颗粒及其膜蛋白的研究，2023-2026，主持

 4. 中国科学院长春应化所电分析国家重点实验室开放课题，无线纳米电极电化学发光传感平台的构建及单细胞内端粒酶活性的研究，2022-2024，主持

 5. 浙江师范大学青年博士专项，聚多巴胺功能化的纳米孔双响应传感平台原位高灵敏检测单个外泌体的研究，2022-2024，主持

 6. 国家自然科学基金面上项目，极性掺杂驱动的G-四链体可塑性调控及结构开关传感器构建，2023-2026，参与

主要研究成果

  1. Dandan Wang; Yong Wang; Haijuan Li; Yanchao Han; Ping Hu; Kongshuo Ma; Mordechai Sheves; Yongdong Jin*, Photoactivated Bacteriorhodopsin/SiNx Nanopore-Based Biological Nanofluidic Generator with Single-Protein Sensitivity, ACS Nano. 2022, 16 (1):1589-1599

   2.  Dandan Wang; Guohua Qi; Ya Zhou; Ying Zhang; Bo Wang; Ping Hu; Yongdong Jin*, Single-Cell ATP Detection and Content Analyses in Electrostimulus-Induced Apoptosis Using Functionalized Glass Nanopipettes, Chemical Communications. 2020, 56 (10): 1561-1564

    3. Dandan Wang; Guohua Qi; Ya Zhou; Haijuan Li; Ying Zhang; Chen Xu; Ping Hu; Yongdong Jin*, Glucose Level Determination in Single Cells in Their Satiety and Starvation States Using an Enzymatic Functional Glass Nanopore, Chemical Communications. 2020, 56 (40): 5393-5396

   4.  Dandan Wang; Xiaolong Xu; Ya Zhou; Haijuan Li; Guohua Qi; Ping Hu; Yongdong Jin*, Short-Chain Oligonucleotide Detection by Glass Nanopore Using Targeting-Induced DNA Tetrahedron Deformation as Signal Amplifier, Analytica Chimica Acta. 2019, 1063 :57-63

   5. Mujing Yang; Rong Lai; Shuzhen Peng; Yun Chang; Xingli Zeng; Dandan Wang*; Xiaoshun Zhou; Yong Shao*, Selectively Recognizing Heptad-Interfaced G-quadruplexes by a Molecular Rotor with an ESIPT Emission. Chemical Communications. 2022, 59 (9):1189-1192

   6. Qiusha Li; Shuzhen Peng; Yun Chang; Mujing Yang; Dandan Wang*; Xiaoshun Zhou; Yong Shao*, A G-triplex-Based Label-Free Fluorescence Switching Platform for the Specific Recognition of Chromium Species. Journal of Photochemistry and Photobiology A: Chemistry. 2022, 432 :114071

   7. Ya Zhou; Dandan Wang; Chuanping Li; Ping Hu; Yongdong Jin*, Resistive-Pulse Sensing and Surface Charge Analysis of a Single Nanoparticle Collision at a Conical Glass Nanopore. Analytical Chemistry. 2019, 91 (12):7648-7653

   8. Kaikai Niu; Qiaozhen Yu; Dandan Wang*; Jianwei Zhao*, Development and Properties of Cyanide-Free Silver-Copper Alloy Coatings via Electrodeposition. Journal of Applied Electrochemistry, 2025

   9. Yong Wang, Dandan Wang, Guohua Qi, Ping Hu, Erkang Wang, and Yongdong Jin*, Glass Nanopipette-Based Plasmonic SERS Platform for Single-Cell MicroRNA-21 Sensing during Apoptosis, Analytical Chemistry. 2023, 95, 16234−16242

   10. Guohua Qi; Dandan Wang; Chuanping Li; Kongshuo Ma; Ying Zhang; Yongdong Jin*, Plasmonic SERS Au Nanosunflowers for Sensitive and Label-Free Diagnosis of DNA Base Damage in Stimulus-Induced Cell Apoptosis. Analytical Chemistry. 2020, 92 (17):11755-11762

   11. Ping Hu; Ying Zhang; Dandan Wang; Guohua Qi; Yongdong Jin*, Glutathione Content Detection of Single Cells under Ingested Doxorubicin by Functionalized Glass Nanopores.Analytical Chemistry. 2021, 93 (9):4240-4245

   12. Ya Zhou; Ruiping Wu; Dandan Wang; Ping Hu; Yongdong Jin*, Single-Molecule Translocation Conformational Sensing of Multiarm DNA Concatemers Using Glass Capillary Nanopore. ACS Sensors. 2019, 4 (12):3119-3123